Blood Flow: Vessels of the primate retina color coded by vessel angle.
Blood Flow: The microvascular network imaged without contrast agents. The movement of single blood cells creates a spatio-temporal flicker. Motion contrast imaging reveals active perfusion in the vessels surrounding the fovea.
Ganglion Cell Function: Fluorescent ring of ganglion cells serving the foveal cones. These cells are expressing the calcium indicator GCaMP, which allows cell responses to be monitored optically.
Two-photon Imaging of the Retina: Reflectance (left) and two-photon excited fluorescence (right) image of the photoreceptor mosaic in the living macaque eye. The main source of fluorescence is most likely all-trans-retinol.
Two-photon Imaging of the Retina: The image shows two-photon excited fluorescence captured from photoreceptors in the living macaque eye where selective S cone damage was induced at different time points.
Blood Flow: A binary mask showing perfused vessels surrounding the fovea of the primate. Vessel angle is coded by color.
- Joseph A, Chu CJ, Feng G, Dholakia K, Schallek J (2020). Label-free imaging of immune cell dynamics in the living retina using adaptive optics. eLife. S2213-6711(20)30240-X. doi: 10.7554/eLife.60547
- Aboualizadeh E, Phillips MJ, McGregor JE, DiLoreto DA Jr, Strazzeri JM, Dhakal KR, Bateman B, Jager LD, Nilles KL, Stuedemann SA, Ludwig AL, Hunter JJ, Merigan WH, Gamm DM, Williams DR (2020). Imaging Transplanted Photoreceptors in Living Nonhuman Primates with Single-Cell Resolution. Stem Cell Reports. S2213-6711(20)30240-X. doi: 10.1016/j.stemcr.2020.06.019. PDF
- Dhakal KR, Walters S, McGregor JE, Schwarz C, Strazzeri JM, Aboualizadeh E, Bateman B, Huxlin KR, Hunter JJ, Williams DR, Merigan WH (2020). Localized Photoreceptor Ablation Using Femtosecond Pulses Focused With Adaptive Optics. Translational Vision Science & Technology(9), 16. PDF